In the following, you can find about 100 peer-reviewed publications that emerged from the MATRICS project! 

2014

• Whelan R. et. al. (2014). Neuropsychosocial profiles of current and future adolescent alcohol misusers. Nature.

• Zuddas A. (2014). The poor outcome of conduct disorders: a need for innovative, more effective therapeutic interventions. European Child and Adolescent Psychiatry.

2015

• Cury C. et. al. (2015). Incomplete Hippocampal Inversion: A Comprehensive MRI Study of Over 2000 Subjects. Frontiers Research Foundation. 

• Ewijk H. et al. (2015). The influence of comorbid oppositional defiant disorder on white matter microstructure in attention-deficit/hyperactivity disorder European Child and Adolescent Psychiatry. 

• French L. et. al., (2015). Early Cannabis Use, Polygenic Risk Score for Schizophrenia and Brain Maturation in Adolescence. JAMA Psychiatry.

• Fritsch V. et al. (2015). Robust regression for large-scale neuroimaging studies. NeuroImage. 

• Hibar D.P. et al. (2015). Common genetic variants influence human subcortical brain structures. Nature. 

• Ortuno-Sierra J. et al. (2015). New evidence of factor structure and measurement invariance of the SDQ across five European nations. European Child and Adolescent Psychiatry.

• Ojelade S.A. et al. (2015). RSU1 regulates ethanol consumption in Drosophila and humans. PNAS. 

• Persico A.M. (2015). Unmet needs in pediatric psychopharmacology: Present scenario and future perspectives. European Neuropsychopharmacology. 

• Richiardi J. et. al. (2015). Correlated gene expression supports synchronous activity in brain networks.nScience.

• Ruggeri B. et al. (2015). Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis. American Journal of Psychiatry. 

• Spechler P.A. et al. (2015). Cannabis use in early adolescence: Evidence of amygdala hypersensitivity to signal of threat. Developmental Cognitive Neuroscience.

• Tzanoulinou S., et. al. (2015). Neuroligin-2 Expression in the Prefrontal Cortex is Involved in Attention Deficits Induced by Peripubertal Stress. Neuropsychopharmacology.

• van der Kooij M.A. et al. (2015). The effects of stress during early postnatal periods on behavior and hippocampal neuroplasticity markers in adult male mice. Neuroscience. 

• Veroude K. et al. (2015). Genetics of aggressive behavior: An overview. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 

2016

• Adriani W. et al. (2016). Commentary on the special issue “The Adolescent Brain”: How can we run operant paradigms in a preclinical adolescent model? Technical tips and future perspectives. Neuroscience and Biobehavioral Reviews. 

• Blair R.J.R.. et al. (2016). Neuro-cognitive system dysfunction and symptom sets: A review of fMRI studies in youth with conduct problems. Neuroscience and Biobehavioral Reviews.  

• Burt K.B. et. al. (2016). Structural brain correlates of adolescent resilience. Journal of Child Psychology and Psychiatry and Allied Disciplines. 

• Cordero M.I. et al. (2016). Effects of paternal and peripubertal stress on aggression, anxiety, and metabolic alterations in the lateral septum. European Neuropsychopharmacology.

• Ewald A. et. al. (2016). The role of the cannabinoid receptor in adolescents′ processing of facial expressions. European Journal of Neuroscience.

• Franke B. et. al. (2016). Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nature Neuroscience. 

• Herpers P.C.M. et. al. (2016). Associations between high callous-unemotional traits and quality of life across youths with non-conduct disorder diagnoses. European Child and Adolescent Psychiatry. 

• Hieab H.H. et. al. (2016). Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience. 

• Holz N.E. et al. (2016). Ventral striatum and amygdala activity as convergence sites for early adversity and conduct disorder. Social Cognitive and Affective Neuroscience. 

• Holz N.E. et al. (2016). Gene x environment interactions in conduct disorder: Implications for future treatments. Neuroscience and Biobehavioral Reviews. 

• Jollans L. et. al. (2016). Ventral Striatum Connectivity During Reward Anticipation in Adolescent Smokers. Developmental Neuropsychology.

• Lancaster T.M. et. al. (2016). Polygenic Risk of Psychosis and Ventral Striatal Activation During Reward Processing in Healthy Adolescents. JAMA Psychiatry. 

• Masi G. et. al. (2016). Psychiatric evaluation of youths with Disruptive Behavior Disorders and psychopathic traits: A critical review of assessment measures. Neuroscience and Biobehavioral Reviews. 

• Mogavero F. et. al. (2016). Clock genes, ADHD and aggression. Neuroscience and Biobehavioral Reviews. 

• Muratori P. et. al. (2016). Moral disengagement and callous-unemotional traits: A longitudinal study of Italian adolescents with a disruptive behaviour disorder. Neuroscience and Biobehavioral Reviews.

• Spinello C. et al. (2016). Pediatric Autoimmune Disorders Associated with Streptococcal Infections and Tourette's Syndrome in Preclinical Studies. Frontiers in Neuroscience. 

• Stacey D. et. al. (2016). A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males. Journal of Psychiatry and Neuroscience.

• Veroude K. et al. (2016). The link between callous-unemotional traits and neural mechanisms of reward processing: An fMRI study. Psychiatry Research - Neuroimaging.

2017

• Bakker M.J. et al. (2017). Practitioner Review: Psychological treatments for children and adolescents with conduct disorder problems – a systematic review and meta-analysis. Journal of Child Psychology and Psychiatry and Allied Disciplines.

• Balia C. et al. (2017). The pharmacological treatment of aggression in children and adolescents with conduct disorder. Do callous-unemotional traits modulate the efficacy of medication? Neuroscience and Biobehavioral Reviews.

• Beaudet G. et. al. (2017). LP-211, a selective 5-HT 7 receptor agonist, increases novelty-preference and promotes risk-prone behavior in rats. Synapse.

• Bing X. et. al. (2017). Impact of a Common Genetic Variation Associated With Putamen Volume on Neural Mechanisms of Attention-Deficit/Hyperactivity Disorder. Journal of the American Academy of Child and Adolescent Psychiatry.

• Bourque J. et. al. (2017). Functional Neuroimaging Predictors of Self-Reported Psychotic Symptoms in Adolescents. American Journal of Psychiatry. 

• Brugman S. et al. (2017). Examining the reactive proactive questionnaire in adults in forensic and non-forensic settings: A variable- and person-based approach. Aggressive Behavior. 

• Cash C. et al. (2017). Poster Viewing Session IV. Journal of Cerebral Blood Flow and Metabolism. 

• Cerniglia L. et al. (2017). Internet Addiction in adolescence: Neurobiological, psychosocial and clinical issues. Neuroscience and Biobehavioral Reviews. 

• Cervesi C. et. al. (2017). Extent, Time Course, and Moderators of Antipsychotic Treatment in Youth With Mood Disorders. Journal of Clinical Psychiatry. 

• Deng W. (2017). Separate neural systems for behavioral change and for emotional responses to failure during behavioral inhibition. Human Brain Mapping.

• Laviola G. et. al. (2017). Low empathy-like behavior in male mice associates with impaired sociability, emotional memory, physiological stress reactivity and variations in neurobiological regulations. PLoS One. 

• Macrì S. et al. (2017). Can laboratory animals violate behavioral norms? Towards a preclinical model of conduct disorder. Neuroscience and Biobehavioral Reviews. 

• Noordermeer S.D.S. et al. (2017). Risk factors for comorbid oppositional defiant disorder in attention-deficit/hyperactivity disorder. European Child and Adolescent Psychiatry. 

• Quinlan B.E. et. al. (2017). Psychosocial Stress and Brain Function in Adolescent Psychopathology. American Journal of Psychiatry. 

• Walker S. et. al. (2017). Constitutive differences in glucocorticoid responsiveness to stress are related to variation in aggression and anxiety-related behaviors. Psychoneuroendocrinology. 

• Zoratto F. et al. (2017). Down-regulation of serotonin and dopamine transporter genes in individual rats expressing a gambling-prone profile: A possible role for epigenetic mechanisms. Neuroscience. 

• Zoratto F. et. al. (2017). Enhanced limbic/impaired cortical-loop connection onto the hippocampus of NHE rats: Application of resting-state functional connectivity in a preclinical ADHD model. Behavioral Brain Research. 

2018

• Adinolfi A. et. al. (2018). Novelty-related behavior of young and adult dopamine transporter knockout rats: Implication for cognitive and emotional phenotypic patterns. Genes, Brain and Behavior. 

• Adriani W. et. al. (2018). Potential for diagnosis versus therapy monitoring of attention deficit hyperactivity disorder: a new epigenetic biomarker interacting with both genotype and auto-immunity. European Child and Adolescent Psychiatry. 

• Bacq A. et. al. (2018). Amygdala GluN2B-NMDAR dysfunction is critical in abnormal aggression of neurodevelopmental origin induced by St8sia2 deficiency. Molecular Psychiatry. 

• Balia C. et. al. (2018). The pharmacological treatment of aggression in children and adolescents with conduct disorder. Do callous-unemotional traits modulate the efficacy of medication? Neuroscience and Biobehavioral Reviews. 

• Bayard F. et. al. (2018). Distinct brain structure and behavior related to ADHD and conduct disorder traits.  Molecular Psychiatry.

• Blair R.J.R. et. al. (2018). Neuro-cognitive system dysfunction and symptom sets: A review of fMRI studies in youth with conduct problems. Neuroscience and Biobehavioral Reviews.

• Bours C.C.A.H. et. al. (2018). Emotional face recognition in male adolescents with autism spectrum disorder or disruptive behavior disorder: an eye-tracking study. European Child and Adolescent Psychiatry. 

• Cinque S. et. al. (2018). Behavioral Phenotyping of Dopamine Transporter Knockout Rats: Compulsive Traits, Motor Stereotypies, and Anhedonia. Genes, Brain and Behavior. 

• da Cruz J. et. al. (2018). Dominant men are faster in decision-making situations and exhibit a distinct neural signal for promptness. Cerebral Cortex. 

• Gonzalez D.A. et. al. (2018). The Arf6 activator Efa6/PSD3 confers regional specificity and modulates ethanol consumption in Drosophila and humans. Molecular Psychiatry.

• Holz N.E. et. al. (2018). Early maternal care may counteract familial liability for psychopathology in the reward circuitry. Social Cognitive and Affective Neuroscience.

• Larrieu T. et.al. (2018). Stress-Induced Depression: Is Social Rank a Predictive Risk Factor? BioEssays.

• Leo D. et. al. (2018). Pronounced Hyperactivity, Cognitive Dysfunctions, and BDNF Dysregulation in Dopamine Transporter Knock-out Rats. Journal of Neuroscience.

• Macrì S. et. al. (2018). Neonatal corticosterone mitigates autoimmune neuropsychiatric disorders associated with streptococcus in mice. Scientific Reports.

• Macrì S. et. al. (2018). Can laboratory animals violate behavioral norms? Towards a preclinical model of conduct disorder. Neuroscience and Biobehavioral Reviews. 

• Masi G. et. al. (2018). Lithium treatment in bipolar adolescents: a follow-up naturalistic study. Neuropsychiatric Disease and Treatment. 

• Mielenz D. et. al. (2018). EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction. Molecular Psychiatry.

• Nemmi F. et. al. (2018). Interaction between striatal volume and DAT1 polymorphism predicts working memory development during adolescence. Developmental Cognitive Neuroscience. 

• Papilloud A. et. al. (2018). Peripubertal stress increases play fighting at adolescence and modulates nucleus accumbens CB1 receptor expression and mitochondrial function in the amygdala. Translational Psychiatry. 

• Ruggeri B. et. al. (2018). Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents. Journal of Child Psychology and Psychiatry and Allied Disciplines.

• Ruisch I.H. et. al. (2018). Maternal substance use during pregnancy and offspring conduct problems: A meta-analysis. Neuroscience and Biobehavioral Reviews.

• Ruisch I.H. et. al. (2018). Pregnancy risk factors in relation to oppositional-defiant and conduct disorder symptoms in the Avon Longitudinal Study of Parents and Children. Journal of Psychiatric Research. 

• Seo S. et. al. (2018). Risk profiles for heavy drinking in adolescence: differential effects of gender.  Addiction Biology. 

• Spechler P.A. et. al. (2018). The initiation of cannabis use in adolescence is predicted by sex-specific psychosocial and neurobiological features. European Journal of Neuroscience. 

• van der Kooij. et. al. (2018). GABA A receptors in the ventral tegmental area control the outcome of social competition in rats. Neuropharmacology. 

• Walker S.E. et. al. (2018). Alterations in brain microstructure in rats that develop abnormal aggression following peripubertal stress. European Journal of Neuroscience. 

• Walker S.E. et. al. (2018). Long-term programming of psychopathology-like behaviors in male rats by peripubertal stress depends on individual’s glucocorticoid responsiveness to stress. Stress: the International Journal on Biology of Stress. 

• Walker S.E. et. al. (2018). The link between aberrant hypothalamic–pituitary–adrenal axis activity during development and the emergence of aggression-animal studies. Neuroscience and Biobehavioral Reviews. 

• Weger M. et. al. (2018). Increased brain glucocorticoid actions following social defeat in rats facilitates the long-term establishment of social subordination. Physiology and Behavior.

• Zoratto F. et. al. (2018). Inside the Developing Brain to Understand Teen Behavior From Rat Models: Metabolic, Structural, and Functional-Connectivity Alterations Among Limbic Structures Across Three Pre-adolescent Stages. Frontiers in Behavioral Neuroscience. 

• Zoratto F. et. al. (2018). Intranasal oxytocin administration promotes emotional contagion and reduces aggression in a mouse model of callousness. Neuropharmacology. 

• Zoratto F. et. al., (2018). Social modulation of risky decision-making in rats (Rattus norvegicus) and tufted capuchin monkeys (Sapajus spp.) Behavioral Brain Research. 

2019

• Adinolfi A. et al. (2019). Behavioral characterization of DAT-KO rats and evidence of asocial-like phenotypes in DAT-HET rats: The potential involvement of norepinephrine system. Behavioral Brain Research.

• Ajmone-Cat M.A. et al. (2019). Brain-Immune Alterations and Mitochondrial Dysfunctions in a Mouse Model of Paediatric Autoimmune Disorder Associated with Streptococcus: Exacerbation by Chronic Psychosocial Stress. Journal of Clinical Medicine.

• Cerniglia L. et al. (2019). Intersections and Divergences Between Empathizing and Mentalizing: Development, Recent Advancements by Neuroimaging and the Future of Animal Modeling. Frontiers in Behavioral Neuroscience.

• Craig M.C. et al. (2019). Distinct associations between fronto-striatal glutamate concentrations and callous-unemotional traits and proactive aggression in disruptive behavior. Cortex.

• Duarte R.R.R. et al. (2019). The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells. Biological Psychiatry.

• Galinowski A. (2019). Heavy drinking in adolescents is associated with change in brainstem microstructure and reward sensitivity. Addiction Biology.

• Huzard D. et al. (2019). Low vagal tone in two rat models of psychopathology involving high or low corticosterone stress responses. Psychoneuroendocrinology.

• Ing A. et al. (2019). Identification of neurobehavioural symptom groups based on shared brain mechanisms. Nature Human Behavior.

• Papilloud A. et al. (2019). Peripubertal stress-induced heightened aggression: modulation of the glucocorticoid receptor in the central amygdala and normalization by mifepristone treatment. Neuropsychopharmacology. 

• Ruisch I.H. et al. (2019). Interplay between genome-wide implicated genetic variants and environmental factors related to childhood antisocial behavior in the UK ALSPAC cohort. European Archives of Psychiatry and Clinical Neuroscience.

• Viana J. et al. (2019). SA69 genetic and epigenetic signatures of aggression in three distinct rodent models. European Neuropsychopharmacology. 

• Zoratto F. et al. (2019). Methylphenidate administration promotes sociability and reduces aggression in a mouse model of callousness. Psychopharmacology.

2020

• Huzard D. et al. (2020). Constitutive differences in glucocorticoid responsiveness are related to divergent spatial information processing abilities. Stress.

• Shum C. (2020). Δ9-tetrahydrocannabinol and 2-AG decreases neurite outgrowth and differentially affects ERK1/2 and Akt signaling in hiPSC-derived cortical neurons. Molecular and Cellular Neuroscience.

• Tistarelli N. et al. (2020). The nature and nurture of ADHD and its comorbidities: A narrative review on twin studies. Neuroscience & Biobehavioral Reviews.